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Study Links Depression to Nearly 80 Genes That Could Shed Light On The Condition

They thought that the genes responsible for triggering depressive symptoms are related to synapses, the cell connectors which transmit electrical and chemical signals.

To test their hypothesis, the scientists conducted a parallel study of genetics data  from 23andMe, a genomics and biotechnology company based in Mountain View, California.

"Depression is a common and often severe condition that affects millions of people worldwide. These new findings help us better understand the causes of depression and show how the UK Biobank study and big data research has helped advance mental health research," said  Dr. Andrew McIntosh, a professor at the University of Edinburgh Center for Clinical Brain Sciences.

Of the identified genes in the study, 78 were associated with broad depression, two genes with probable MDD, and one gene with ICD-coded MDD. The researchers wrote that broad depression may include types of personality or psychiatric disorders , while MDD and ICD-coded MDD "offer more robust definitions for depression."

Depression Test - Bookshelf


The Effects of Depression, Test Artifacts, and Sex on Neuropsychological Test
98 pages
The Effects of Depression, Test Artifacts, and Sex on Neuropsychological Test


Applied Statistics: From Bivariate Through Multivariate Techniques, From Bivariate Through Multivariate Techniques
1172 pages
Applied Statistics: From Bivariate Through Multivariate Techniques, From Bivariate Through Multivariate Techniques

For now, consider the following example: If a researcher wants to evaluate whether a new measure of depression really does assess depression, he or she would need to collect data to see if scores on the new depression measure are related to behaviors, group memberships, and test scores in a manner that would make sense if the test really measures depression. For example, scores on the new depression test should predict behaviors that are associated with depression, such as ...

Sex Differences in Depression, A Test of Alternative Explanations for the Greater Vulnerability of Women to Depression
686 pages
Sex Differences in Depression, A Test of Alternative Explanations for the Greater Vulnerability of Women to Depression


Late-Life Depression
420 pages
Late-Life Depression

TABLE 10.4. Abbreviated Neuropsychological Test Battery to Identify Cognitive Deficits in Depression Wechsler Abbreviated Scale of Intellelligence (WASI), Wechsler Test of Adult Reading (WTAR) Trail Making Test A, Digit Span, Letter Number Sequencing FAS Controlled Oral Word Association Test (FAS-COWAT), Animal Naming Test (ANT), Boston Naming Test (BNT) Matrix Reasoning, Block Design, Rey-Osterreith Complex Figure Test California Verbal Learning Test-II ( CVLT-II), ...

Treatment Plans and Interventions for Depression and Anxiety Disorders, 2e
490 pages
Treatment Plans and Interventions for Depression and Anxiety Disorders, 2e

FORM 4.9. FORMS Intake Form Quick Inventory of Depressive Symptomatology — Self-Report (QIDS-SR16 ) Evaluation of Depression: Test Scores, Substance Use, History, and Recommendations Cognitive, Behavioral, and Interpersonal Assessment of Depression Evaluation of Suicidal Risk No-Suicide Contract Information for Patients about Depression Patient's Weekly Activity Schedule Patient's Weekly Planning Schedule: Predicting Pleasure and Mastery Patient's Daily Record of ...

Depression Test - News


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