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Meta-analysis finds omega-3 supplements provide little benefit

Omega-3 supplements may not protect a patient from heart disease or vascular events, according to a meta-analysis published in JAMA Cardiology .

Consumption of omega-3 fatty acids found in fish has been reported to lower the risk of death from coronary heart disease (CHD) in observational studies, according to Theingi Aung, MBBS, and colleagues—but randomized trials of omega-3 supplements have produced varying results.

Aung et al. pulled data from 10 randomized studies containing 77,917 participants (61.4 percent men; average age 64 at baseline) lasting an average of 4.4 years.

Compared to control groups, individuals taking supplements had risk reductions of 7 percent for CHD death, 3 percent for nonfatal myocardial infarction and 4 percent for any CHD events. However, none of the associations reached statistical significance.

“The results provide no support for current recommendations to use omega-3 fatty acid supplements for the prevention of fatal coronary heart disease or any cardiovascular disease in people who have or (are) at high risk of developing cardiovascular disease,” the researchers wrote.

Atherosclerosis Supplements - Bookshelf


Atherosclerosis: New Insights for the Healthcare Professional: 2013 Edition
583 pages
Atherosclerosis: New Insights for the Healthcare Professional: 2013 Edition

For more information on this research see: Regular lipoprotein apheresis maintains residual cardiovascular and microvascular function in patients with advanced atherosclerotic disease. Atherosclerosis Supplements, 2013;14(1):135 -141. Atherosclerosis Supplements can be contacted at: Elsevier Ireland Ltd, Elsevier House, Brookvale Plaza, East Park Shannon, Co, Clare, 00000, Ireland. The news editors report that additional information may be obtained by contacting M. Reimann, ...

Atherosclerosis: New Insights for the Healthcare Professional: 2011 Edition
352 pages
Atherosclerosis: New Insights for the Healthcare Professional: 2011 Edition

The publisher of the journal Atherosclerosis Supplements can be contacted at: Elsevier Ireland Ltd., Elsevier House, Brookvale Plaza, East Park Shannon, Co. Clare, Ireland. (2010 APR 5) Research reports on life sciences from RR. Koenen and colleagues provide new insights Researchers detail in 'Therapeutic targeting of chemokine interactions in atherosclerosis,' new data in life sciences. According to recent research from Aachen, Germany, “Atherosclerosis is a chronic ...

Issues in Histology and Circulatory Medicine: 2013 Edition
271 pages
Issues in Histology and Circulatory Medicine: 2013 Edition

According to the news reporters, the research concluded: “PEX is applicable in subjects with very low body weight when the extreme severity of the clinical picture has no therapeutic alternatives.” For more information on this research see: A three month-old infant with severe hyperchylomicronemia: Molecular diagnosis and extracorporeal treatment. Atherosclerosis Supplements, 2013;14(1 ):7376. Atherosclerosis Supplements can be contacted at: Elsevier Ireland Ltd, Elsevier House, ...

Dietary Supplements in Health Promotion
405 pages
Dietary Supplements in Health Promotion

2005. Dietary polyphenols decrease glucose uptake by human intestinal caco-2 cells. FEBS Letters 579 (7) (March): 1653–1657. Jones, Dean P. 2006. Redefining oxidative stress. Antioxidants and Redox Signaling 8 (9–10) (October ): 1865–1879. Kapetivadze, V., R. Tabukashvili, K. Tchaava, N. Gegeshidze, Z. Grigorashvili, and I. Kapetivadze. 2010. Ms423 treatment of atherosclerosis patients with type 2 diabetes by soybean flavonoid supplements and indapamide . Atherosclerosis ...

Lipids—Advances in Research and Application: 2013 Edition, ScholarlyBrief
372 pages
Lipids—Advances in Research and Application: 2013 Edition, ScholarlyBrief

According to the news editors, the research concluded: “Lipoprotein apheresis therapy is important for the reduction of cardiovascular events, but optimization of additional modifiable risk factors should also be undertaken.” For more information on this research see: Factors inducing cardiovascular events in patients treated by lipoprotein apheresis. Atherosclerosis Supplements, 2013;l4(l ):45-50. Atherosclerosis Supplements can be contacted at: Elsevier Ireland Ltd, Elsevier House, ...

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